Acute Acepromazine Overdose: Clinical Effects and Toxicokinetic Evaluation
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چکیده
منابع مشابه
Intentional overdose with insulin: prognostic factors and toxicokinetic/toxicodynamic profiles
INTRODUCTION Prognostic factors in intentional insulin self-poisoning and the significance of plasma insulin levels are unclear. We therefore conducted this study to investigate prognostic factors in insulin poisoning, in relation to the value of plasma insulin concentration. METHODS We conducted a prospective study, and used logistic regression to explore prognostic factors and modelling to ...
متن کاملClinical and ECG effects of escitalopram overdose.
STUDY OBJECTIVE We investigate the clinical effects of escitalopram overdose and determine the risk of QT prolongation and serotonin toxicity. METHODS A review of escitalopram overdoses to a clinical toxicology unit was undertaken. Patient demographics, details of the ingestion, clinical effects, including evidence of serotonin toxicity, complications (arrhythmias and seizures), ICU admission...
متن کاملModerate toxic effects following acute zonisamide overdose.
Zonisamide is an antiepileptic drug that acts on voltage-sensitive sodium and calcium channels, with a modulatory effect on GABA-mediated neuronal inhibition and an inhibitory effect on carbonic anhydrase. It is used mainly for the treatment of partial seizures, and is generally well tolerated at therapeutic doses. The most common reported adverse effects are somnolence, anorexia, dizziness, an...
متن کاملAcute Exenatide Overdose
Exenatide, a glucagon-like peptide-1 (GPL-1) receptor agonist, was quite recently approved as adjunctive therapy to improve glycemia control in type 2 diabetes patients. There is very limited information on overdose consequences. We report 3 cases of exenatide overdose involving 2 suicidal self-injections associated with psychotropic intake and one medication error. Two patients rapidly experie...
متن کاملEvaluation of Prothrombin Time in Acute Acetaminophen Overdose treated by N-acetylcysteine
Background: Acetaminophen (N-Acetyl-p aminophenol; APAP) is one of the most common types of analgesics. It is also the most common xneobitic reported to poison centers. This study investigates if therapeutic doses of NAC can falsely increase coagulation tests, prothrombin time (PT) and bleeding time (BT). Methods: Thirty-six APAP poisoned patients whose acetaminophen serum concentration were...
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ژورنال
عنوان ژورنال: Journal of Medical Toxicology
سال: 2014
ISSN: 1556-9039,1937-6995
DOI: 10.1007/s13181-014-0416-1